Mefenamic acid-13C6 is a stable isotope-labeled derivative of Mefenamic acid, a non-steroidal anti-inflammatory drug (NSAID) that penetrates the blood-brain barrier. It functions as a competitive inhibitor of human cyclooxygenase-1 (hCOX-1) and human cyclooxygenase-2 (hCOX-2), with reported IC50 values of 40 nM and 3 μM, respectively. This reagent is valuable for metabolic studies and pharmacokinetic research involving the behavior of Mefenamic acid in biological systems.
Mefenamic acid-13C6 is a stable isotope-labeled derivative of Mefenamic acid, a non-steroidal anti-inflammatory drug (NSAID) that penetrates the blood-brain barrier. It functions as a competitive inhibitor of human cyclooxygenase-1 (hCOX-1) and human cyclooxygenase-2 (hCOX-2), with reported IC50 values of 40 nM and 3 μM, respectively. This reagent is valuable for metabolic studies and pharmacokinetic research involving the behavior of Mefenamic acid in biological systems.
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