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MEK ligand-2

Ligand for Target Protein for PROTAC

MEK ligand-2 is a ligand specifically designed for PROTAC applications targeting MEK1 and MEK2 proteins. This compound serves as a vital component for the development of the MS934 PROTAC, facilitating the degradation of MEK1 and MEK2 via a VHL-recruiting mechanism. It plays a crucial role in research aimed at understanding the regulation of MAPK signaling pathways and potential therapeutic strategies in cancer biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	212631-56-6
Applications	Ligand for Target Protein for PROTAC
Formula	C₁₃H₈F₃IN₂O₂
Molecular Weight	408.11
SMILES	ONC(C1=C(C(F)=C(C=C1)F)NC2=C(C=C(C=C2)I)F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.