Memantine-d3 hydrochloride

Catalog No.: A67306
Stable Isotope
Memantine-d3 hydrochloride is a deuterium-labeled analog of Memantine, a noncompetitive antagonist of the N-methyl-D-aspartate receptor (NMDAR). This stable isotope is utilized in research on moderate-to-severe Alzheimer's disease (AD), providing insights into the pharmacokinetics and action of Memantine in a biological context. Memantine's mechanism of action allows for the exploration of glutamatergic signaling pathways relevant to neurodegenerative diseases.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMemantine-d3 hydrochloride is a deuterium-labeled analog of Memantine, a noncompetitive antagonist of the N-methyl-D-aspartate receptor (NMDAR). This stable isotope is utilized in research on moderate-to-severe Alzheimer's disease (AD), providing insights into the pharmacokinetics and action of Memantine in a biological context. Memantine's mechanism of action allows for the exploration of glutamatergic signaling pathways relevant to neurodegenerative diseases.
Product Information
Catalog NumA67306
FormulaC12H19D3ClN
Molecular Weight218.78
CAS Number1329802-06-3
SMILESN[C@]1(C2)C[C@]3(C)C[C@@H](C[C@@]2(C([2H])([2H])[2H])C3)C1.[H]Cl
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