Fig. 1 · Structure
Documents & Downloads
Memantine-d6 hydrochloride
Stable Isotope
Memantine-d6 hydrochloride is a deuterium-labeled analog of Memantine hydrochloride, functioning primarily as a stable isotope in research. Memantine acts as an uncompetitive antagonist of the NMDA receptor, exhibiting moderate affinity, and also inhibits the cytochrome P450 enzymes CYP2B6 and CYP2D6 with inhibition constants of 0.51 nM and 94.9 μM, respectively. This compound is invaluable for studies involving neuropharmacology, metabolic profiling, and isotope labeling in drug development and mechanistic investigations.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1189713-18-5 |
| Applications | Stable Isotope |
| Formula | C12H16D6ClN |
| Molecular Weight | 221.80 |
| SMILES | [2H]C([2H])([2H])[C@@](C[C@@](N)(C[C@@H]1C2)C3)(C1)C[C@@]32C([2H])([2H])[2H].Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.