Fig. 1 · Structure
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MenA-IN-2
MenA Inhibitor
MenA-IN-2 is a potent inhibitor of 1,4-dihydroxy-2-naphthoate prenyltransferase (MenA), demonstrating an IC50 value of 22 µM. This compound effectively inhibits Mycobacterium tuberculosis (Mtb) with a GIC50 value of 10 µM, contributing to the inhibition of Mtb transmission. MenA-IN-2 serves as a valuable tool in the research of tuberculosis treatment and the development of antimicrobial strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3026690-49-0 |
| Applications | MenA Inhibitor |
| Formula | C23H31ClN2O |
| Molecular Weight | 386.96 |
| SMILES | CCCN(C1=CC=C(C=C1)CN2CCC(CC2)COC3=CC=C(C=C3)Cl)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.