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Menin-MLL-IN-35

Menin/MLL Protein/protein Interaction Inhibitor

Menin-MLL-IN-35 is a potent inhibitor of the menin/MLL protein-protein interaction, exhibiting an IC50 value of 0.096 μM in the modulation of MEIS1 mRNA expression. This compound is valuable for cancer research, particularly in the context of myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPN), and diabetes. Its ability to disrupt key molecular interactions makes it a promising tool for investigating therapeutic strategies targeting these conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2654080-48-3
Applications	Menin/MLL Protein/protein Interaction Inhibitor
Formula	C₃₁H₄₈FN₇O₃
Molecular Weight	585.76
SMILES	OCCN(C)CCC[C@@H](N1CC2(CN(C3=NC=NN=C3OC4=C(C=C(C=C4)F)C(N(CC)C(C)C)=O)CC2)C1)C(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.