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Menin-MLL-IN-36

Menin/MLL Protein/protein Interaction Inhibitor

Menin-MLL-IN-36 is a potent inhibitor of the menin/MLL protein/protein interaction, demonstrating an IC50 value of 0.043 μM in MEIS1 mRNA expression assays. This compound is valuable for studying the molecular mechanisms underlying various diseases, including cancer, myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPN), and diabetes. Its role in disrupting critical protein interactions makes it a significant tool for research into targeted therapies and disease pathogenesis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2654078-52-9
Applications	Menin/MLL Protein/protein Interaction Inhibitor
Formula	C₂₉H₄₄FN₇O₂
Molecular Weight	541.70
SMILES	CNCCC[C@H](C(C)C)N1CC2(CN(CC2)C3=NC=NN=C3OC4=C(C(N(C(C)C)CC)=O)C=C(F)C=C4)C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.