Fig. 1 · Structure

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Menin-MLL inhibitor 31

Menin-MLL Inhibitor

Menin-MLL inhibitor 31 is a potent inhibitor of the menin-MLL interaction, exhibiting an IC50 value of 4.6 nM. This compound is instrumental in studying the role of menin in mixed-lineage leukemia and other related malignancies. Its targeted inhibition is valuable for research applications focused on identifying therapeutic strategies for leukemia and understanding underlying molecular mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2863656-86-2
Applications Menin-MLL Inhibitor
Formula C77H119FN28O14
Molecular Weight 1679.95
SMILES
O=C1C2(NC(=O)[C@]3(N(C(=O)[C@H](CC4=CC(F)=CC=C4)NC(=O)[C@@H](NC([C@H](CC=5C=6C(NC5)=CC=CC6)NC([C@@H](NC([C@@H](NC(C)=O)C)=O)CCCNC(=N)N)=O)=O)CCCC[C@@H](C(=O)N7C[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCN)=O)CC7)N1)CCC3)[H])CCC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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