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Menin-MLL inhibitor 34

Menin-MLL Inhibitor

Menin-MLL Inhibitor 34 targets the Menin-MLL complex, demonstrating selective and potent inhibition with an IC50 of 18.21 nM. This compound exhibits sustained anti-leukemic effects by decreasing Menin protein levels and down-regulating MEN1 transcription. It is valuable for research in hematologic malignancies, particularly in understanding the role of the Menin-MLL interaction in leukemia progression and therapeutic response.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3096376-30-3
Applications	Menin-MLL Inhibitor
Formula	C₄₀H₅₄FN₉O₄S
Molecular Weight	775.98
SMILES	O=C(N(CC)C(C)C)C1=CC(F)=CC=C1NC2=CN=CN=C2N3CCN(CC4CN(C5=CC=C(S(=O)(C6CN(C(/C=C/CN(C)C)=O)C6)=O)C=C5)C4)C(C)C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.