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MEPB

AR Modulator

MEPB is a selective modulator of the androgen receptor (AR) that targets the AF-2 domain. It enhances the binding of co-repressors to AR by specifically interacting with the BF3 pocket, thereby influencing co-regulator dynamics. Research indicates that MEPB mitigates degeneration in models of spinal bulbar muscular atrophy, demonstrating its potential in neurodegenerative disease studies and AR-related pathologies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	331948-99-3
Applications	AR Modulator
Formula	C₂₄H₂₄N₂O₂S
Molecular Weight	404.52
SMILES	CC1=CC=C(OCCN2C3=CC=CC=C3N=C2SCCOC4=CC=CC=C4)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.