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Mepolizumab
Mepolizumab (SB 240563) is a humanized monoclonal antibody designed to specifically bind to and neutralize interleukin-5 (IL-5). IL-5 is a critical cytokine that regulates eosinophil proliferation, activation, and survival. This antibody is utilized in research focused on eosinophilic conditions, including eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma, providing a valuable tool for investigating the pathophysiology and potential therapeutic interventions for these diseases.
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Cat. No.
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 196078-29-2 |
| Molecular Weight | 146240 |
| Synonyms | SB 240563 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.