Fig. 1 · Structure
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Mesoridazine benzenesulfonate
Antipsychotic Agent
Mesoridazine benzenesulfonate is an orally active phenothiazine antipsychotic agent that acts primarily by blocking human ether-a-go-go related gene (hERG) channels. It demonstrates potent inhibitory activity with an IC50 of 550 nM at 0 mV in human embryonic kidney 293 cells. This compound is valuable for research into schizophrenia and other psychiatric disorders, providing insights into antipsychotic mechanisms and the modulation of hERG channel activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 32672-69-8 |
| Applications | Antipsychotic Agent |
| Formula | C27H32N2O4S3 |
| Molecular Weight | 544.75 |
| Synonyms | TPS-23 benzenesulfonate |
| SMILES | O=S(C(C=C1N2CCC3N(C)CCCC3)=CC=C1SC4=C2C=CC=C4)C.O=S(C5=CC=CC=C5)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.