Fig. 1 · Structure
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MET kinase-IN-2
MET Kinase Inhibitor
MET kinase-IN-2 is a selective inhibitor of MET kinase, exhibiting a potent IC50 of 7.4 nM. This compound demonstrates significant antitumor activity, making it a valuable tool for cancer research. Its oral bioavailability enhances its utility in preclinical studies aimed at understanding MET-driven malignancies and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2101241-90-9 |
| Applications | MET Kinase Inhibitor |
| Formula | C33H27FN4O4 |
| Molecular Weight | 562.59 |
| SMILES | O=C1C(C2=CC=CC=C2)=CNC3=C1C(NC4=CC=C(OC5=CC=NC6=CC(OCC(C)(O)C)=CC=C56)C(F)=C4)=NC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.