Fig. 1 · Structure
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MET kinase-IN-4
Met Kinase Inhibitor
MET kinase-IN-4 is a selective inhibitor of Met kinase, exhibiting potent inhibitory activity with an IC50 value of 1.9 nM. This compound is designed for research applications targeting Met signaling pathways, particularly in the context of cancer biology. MET kinase-IN-4 serves as a valuable tool for studying the role of Met kinase in tumorigenesis and the potential therapeutic benefits of targeting this pathway.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 888719-03-7 |
| Applications | Met Kinase Inhibitor |
| Formula | C25H16F2N4O3 |
| Molecular Weight | 458.42 |
| SMILES | O=C(C1=CC=CN(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=C5C(NC=C5)=NC=C4)C(F)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.