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Metabolex-36

Catalog No.: A60380
FFA4 Agonist
Metabolex-36 is a potent agonist of the free fatty acid receptor 4 (FFA4), demonstrating a pEC50 value of 5.9. In contrast, it exhibits a significantly lower activity for FFA1, with a pEC50 value of less than 4.0. This compound is crucial for studies focused on metabolic regulation and the modulation of inflammatory pathways, making it a valuable tool in research related to obesity, diabetes, and cardiovascular diseases.
Metabolex-36 1224102-50-4 FFA4 Agonist
Grouped product items
Size Price Stock Qty
25mg
$1,405.00
In stock
50mg
$1,790.00
In stock
100mg
$2,240.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMetabolex-36 is a potent agonist of the free fatty acid receptor 4 (FFA4), demonstrating a pEC50 value of 5.9. In contrast, it exhibits a significantly lower activity for FFA1, with a pEC50 value of less than 4.0. This compound is crucial for studies focused on metabolic regulation and the modulation of inflammatory pathways, making it a valuable tool in research related to obesity, diabetes, and cardiovascular diseases.
Product Information
Catalog NumA60380
FormulaC21H19ClF2N2O3
Molecular Weight420.84
CAS Number1224102-50-4
SMILESO=C(O)C(C)CC1=CC(F)=C(OCC2=CC(C)=NN2C3=CC=C(Cl)C=C3)C(F)=C1
SynonymsMet-36
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > Free Fatty Acid Receptor (FFAR)