Fig. 1 · Structure
Documents & Downloads
Metformin-d6 hydrochloride
Stable Isotope
Metformin-d6 hydrochloride is a stable isotope-labeled form of Metformin hydrochloride, primarily targeting the mitochondrial respiratory chain. It is known for its ability to activate AMPK, thereby enhancing insulin sensitivity and providing insights into type 2 diabetes research. Additionally, Metformin-d6 hydrochloride mitigates oxidative and nitrosative stress, inflammation, and apoptosis associated with liver ischemia/reperfusion injury. The compound also influences autophagy-related protein expression by modulating the mTOR signaling pathway, facilitating tumor cell autophagy, and exerting anti-tumor effects in renal cell carcinoma models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1185166-01-1 |
| Applications | Stable Isotope |
| Formula | C4H6D6ClN5 |
| Molecular Weight | 171.66 |
| Synonyms | 1,1-Dimethylbiguanide-d6 hydrochloride |
| SMILES | NC(NC(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=N)=N.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.