Fig. 1 · Structure

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Methoctramine

M2 Muscarinic Receptor Antagonist

Methoctramine is a selective antagonist of the M2 muscarinic receptor, exhibiting potent cardioselectivity. This compound effectively inhibits muscarine-induced bradycardia in vivo, making it a valuable tool for investigating cardiovascular mechanisms. Methoctramine is utilized in research focused on cardiovascular diseases, contributing to the understanding of muscarinic receptor activity and its implications in cardiac health.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 104807-40-1
Applications M2 Muscarinic Receptor Antagonist
Formula C36H62N4O2
Molecular Weight 582.90
SMILES
COC1=CC=CC=C1CNCCCCCCNCCCCCCCCNCCCCCCNCC2=CC=CC=C2OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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