Fig. 1 · Structure
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Methopterin
Bone Resorption Inhibitor
Methopterin is a potent inhibitor of osteoclast activity, primarily targeting pathways involved in bone resorption. This compound effectively suppresses the proliferation and activation of osteoclasts, leading to a reduction in bone resorption and promoting osteoclast apoptosis. Methopterin is utilized in research applications focused on osteoporosis, arthritis, and other conditions associated with excessive bone loss.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2410-93-7 |
| Applications | Bone Resorption Inhibitor |
| Formula | C20H21N7O6 |
| Molecular Weight | 455.42 |
| SMILES | O=C(CC[C@H](NC(C1=CC=C(C=C1)N(C)CC2=CN=C3NC(N)=NC(C3=N2)=O)=O)C(O)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.