• Sign In
  • FAQ
  • Create an Account
Currency
USD currency flagUSD
Toggle Nav
My Cart
Menu
Account
Settings
Currency
USD currency flagUSD

Methotrexate metabolite-d3

Catalog No.: A54041
Stable Isotope
Methotrexate metabolite-d3 is a deuterium-labeled form of the active Methotrexate metabolite known as DAMPA. This compound serves as a folic acid antagonist, playing a crucial role in inhibiting dihydrofolate reductase, which is critical for nucleotide synthesis. Methotrexate metabolite-d3 is utilized in various research applications, including pharmacokinetic studies and metabolic profiling, to better understand the dynamics of Methotrexate metabolism and its therapeutic effects.
Methotrexate metabolite-d3 1794780-00-9 Stable Isotope
Grouped product items
Size Price Stock Qty
2.5mg
$500.00
In stock
Bulk Size
Bulk Discount
Bulk Inquiry
Notify me when the price drops
Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMethotrexate metabolite-d3 is a deuterium-labeled form of the active Methotrexate metabolite known as DAMPA. This compound serves as a folic acid antagonist, playing a crucial role in inhibiting dihydrofolate reductase, which is critical for nucleotide synthesis. Methotrexate metabolite-d3 is utilized in various research applications, including pharmacokinetic studies and metabolic profiling, to better understand the dynamics of Methotrexate metabolism and its therapeutic effects.
Product Information
Catalog NumA54041
FormulaC15H12D3N7O2
Molecular Weight328.34
CAS Number1794780-00-9
SMILESNC1=NC(N)=NC2=C1N=C(CN(C3=CC=C(C=C3)C(O)=O)C([2H])([2H])[2H])C=N2
SynonymsDAMPA-d3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

Isotope-Labeled Compounds