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Methoxamine

α1-Adrenoceptor Agonist

Methoxamine is a selective α1-adrenoceptor agonist that mediates vasoconstriction and enhances peripheral vascular resistance. This compound is pertinent in cardiovascular research, as it facilitates the overflow of ATP, ADP, and AMP in the rabbit pulmonary artery through a prazosin-sensitive mechanism, while not affecting adenosine levels. Methoxamine is valuable for studies investigating adrenergic signaling and vascular tone regulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	390-28-3
Applications	α1-Adrenoceptor Agonist
Formula	C₁₁H₁₇NO₃
Molecular Weight	211.26
SMILES	COC1=CC=C(C(C(C(N)C)O)=C1)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.