Fig. 1 · Structure
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Methyclothiazide
Antihypertensive Agent
Methyclothiazide is an orally active antihypertensive agent that primarily functions as a diuretic. It effectively reduces vascular responsiveness to endogenous vasoconstrictors, including norepinephrine, thereby contributing to blood pressure regulation. Additionally, Methyclothiazide exhibits inhibitory effects on voltage-dependent calcium channel (VDCC) activity in vitro, making it a valuable tool for cardiovascular research and the study of hypertension mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 135-07-9 |
| Applications | Antihypertensive Agent |
| Formula | C9H11Cl2N3O4S2 |
| Molecular Weight | 360.24 |
| SMILES | O=S(C1=C(Cl)C=C(C2=C1)NC(CCl)N(C)S2(=O)=O)(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.