Fig. 1 · Structure
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Methyl-4-oxoretinoate
ODC Inhibitor
Methyl-4-oxoretinoate is an inhibitor of ornithine decarboxylase (ODC), a key enzyme involved in polyamine synthesis. This compound effectively inhibits TPA-induced ODC activity and reduces carcinogen-induced papilloma formation in mouse skin models. It serves as a valuable tool in cancer research, particularly in studies focusing on skin carcinogenesis and the modulation of polyamine metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 38030-58-9 |
| Applications | ODC Inhibitor |
| Formula | C21H28O3 |
| Molecular Weight | 328.45 |
| SMILES | COC(/C=C(C)/C=C/C=C(C)/C=C/C(C(C)(CC1)C)=C(C)C1=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.