Methylisothiazolinone-d3 hydrochloride is a deuterium-labeled derivative of Methylisothiazolinone hydrochloride, serving as a stable isotope for research applications. It acts as a bacterial and fungal inhibitor and preservative, while also functioning as a sensitizer. This compound is known to activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells, leading to apoptosis and an inflammatory response. Additionally, Methylisothiazolinone can promote atopic dermatitis development in murine models by interfering with Th2/Th17 immune pathways and can induce mitochondrial damage in the endothelium of rat cerebral blood vessels.
Methylisothiazolinone-d3 hydrochloride is a deuterium-labeled derivative of Methylisothiazolinone hydrochloride, serving as a stable isotope for research applications. It acts as a bacterial and fungal inhibitor and preservative, while also functioning as a sensitizer. This compound is known to activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells, leading to apoptosis and an inflammatory response. Additionally, Methylisothiazolinone can promote atopic dermatitis development in murine models by interfering with Th2/Th17 immune pathways and can induce mitochondrial damage in the endothelium of rat cerebral blood vessels.
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