Metoclopramide-d3 is a deuterium-labeled derivative of Metoclopramide. This compound functions as a potent antagonist of the 5-HT3 and dopamine D2 receptors, exhibiting IC50 values of 308 nM and 483 nM, respectively. Metoclopramide-d3 is utilized in research focusing on nausea, vomiting, gastroesophageal reflux disease, and gastroparesis, providing a valuable tool for studying the pharmacokinetics and dynamics of this important therapeutic agent.
Metoclopramide-d3 is a deuterium-labeled derivative of Metoclopramide. This compound functions as a potent antagonist of the 5-HT3 and dopamine D2 receptors, exhibiting IC50 values of 308 nM and 483 nM, respectively. Metoclopramide-d3 is utilized in research focusing on nausea, vomiting, gastroesophageal reflux disease, and gastroparesis, providing a valuable tool for studying the pharmacokinetics and dynamics of this important therapeutic agent.
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