Fig. 1 · Structure
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Metyrapone Tartrate
11β-hydroxylase Inhibitor
Metyrapone Tartrate is a potent inhibitor of 11β-hydroxylase, effectively decreasing endogenous adrenal corticosteroid synthesis and lowering glucocorticoid levels. This compound also serves as an autophagy activator by downregulating the mTOR pathway, enhancing the efficiency of the autophagic process. Metyrapone Tartrate is utilized in research applications related to Cushing's syndrome and depression, providing insights into the regulation of aldosterone production and the modulation of behavior and emotional response.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 908-35-0 |
| Applications | 11β-hydroxylase Inhibitor |
| Formula | C22H26N2O13 |
| Molecular Weight | 526.45 |
| Synonyms | Su-4885 Tartrate |
| SMILES | CC(C)(C(C1=CC=CN=C1)=O)C2=CC=CN=C2.O=C([C@@H]([C@H](C(O)=O)O)O)O.O=C([C@@H]([C@H](C(O)=O)O)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.