Fig. 1 · Structure

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MeV-IN-1

MeV Inhibitor

MeV-IN-1 is a selective inhibitor of Measles virus (MeV) entry, exhibiting an IC50 of 100 µM and a notable IC50 of 55 µM against live MeV-Edm. It effectively inhibits the formation of infectious centers while demonstrating minimal cytotoxicity in treated cells. MeV-IN-1 disrupts R18 redistribution in cells expressing MV-H and MV-F proteins, thereby preventing membrane fusion and viral entry. This compound is valuable for studying MeV pathogenesis and developing antiviral strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 313527-44-5
Applications MeV Inhibitor
Formula C14H12N2O
Molecular Weight 224.26
Synonyms OX-1
SMILES
NC1=CC=C(OC(CC2=CC=CC=C2)=N3)C3=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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