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Mezagitamab
Mezagitamab (TAK-079) is an IgG1λ monoclonal antibody targeting CD38. This antibody facilitates the depletion of tumor cells that express CD38 via mechanisms of antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). It is currently being investigated for its therapeutic potential in treating conditions such as relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP), demonstrating significant relevance in clinical research settings focused on hematologic malignancies and autoimmune disorders.
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Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2227490-52-8 |
| Molecular Weight | 143700 |
| Synonyms | TAK-079 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.