Fig. 1 · Structure
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Mezilamine
Antidopaminergic Agent
Mezilamine is a potent antidopaminergic agent primarily targeting α-adrenoceptors. It induces a concentration-dependent enhancement of electrically stimulated 3H-noradrenaline overflow in rat cortical slices, while showing no impact on basal overflow levels. Mezilamine functions as a presynaptic α-adrenoceptor antagonist and a postsynaptic α-adrenoceptor agonist, making it a valuable tool for research into neuropharmacology and neurotransmitter modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 50335-55-2 |
| Applications | Antidopaminergic Agent |
| Formula | C11H18ClN5S |
| Molecular Weight | 287.81 |
| SMILES | CSC1=C(N2CCN(C)CC2)N=C(NC)N=C1Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.