Fig. 1 · Structure
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MG624
nAChR Antagonist
MG624 is a potent and selective antagonist of the neuronal α7 nicotinic acetylcholine receptor (nAChR), exhibiting a Ki value of 106 nM. This compound primarily inhibits α7 nAChR-mediated signaling, making it a valuable tool for research investigating cholinergic neurotransmission and related neurological disorders. MG624 can be utilized in studies exploring the role of α7 nAChR in synaptic plasticity, cognitive function, and neurodegenerative disease mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 77257-42-2 |
| Applications | nAChR Antagonist |
| Formula | C22H30INO |
| Molecular Weight | 451.38 |
| Synonyms | Stilonium iodide |
| SMILES | CC[N+](CC)(CC)CCOC1=CC=C(/C=C/C2=CC=CC=C2)C=C1.[I-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.