Fig. 1 · Structure
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MGAT2-IN-2
Acyltransferase Inhibitor
MGAT2-IN-2 is a highly selective inhibitor of acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2), demonstrating an IC50 of 3.4 nM. This compound is instrumental in studying lipid metabolism and associated metabolic disorders, making it valuable for research in obesity and diabetes. Its potent inhibitory activity offers potential avenues for therapeutic development targeting MGAT2.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1710630-11-7 |
| Applications | Acyltransferase Inhibitor |
| Formula | C26H21F5N4O4S |
| Molecular Weight | 580.53 |
| SMILES | O=C(N1CCC2=C1C(N3C(CCC3)=O)=CC(S(=O)(NC4=CC=C(F)C=C4F)=O)=C2)NC5=CC=C(C(F)(F)F)C=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.