mGluR2 antagonist 1 is a selective negative allosteric modulator of the metabotropic glutamate receptor 2 (mGluR2) with an IC50 of 9 nM. This compound demonstrates high potency and oral bioavailability, coupled with excellent brain permeability. It is primarily utilized in research focused on neurological disorders, providing insights into glutamatergic signaling and potential therapeutic interventions.
mGluR2 antagonist 1 is a selective negative allosteric modulator of the metabotropic glutamate receptor 2 (mGluR2) with an IC50 of 9 nM. This compound demonstrates high potency and oral bioavailability, coupled with excellent brain permeability. It is primarily utilized in research focused on neurological disorders, providing insights into glutamatergic signaling and potential therapeutic interventions.
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