Fig. 1 · Structure
Documents & Downloads
mGluR2 modulator 1
mGluR2 Modulator
mGluR2 modulator 1 is a potent positive allosteric modulator of the metabotropic glutamate receptor-2 (mGluR2), exhibiting an EC50 of 0.03 μM and effective blood-brain barrier penetration. This compound is valuable for investigating the role of mGluR2 in neuropsychiatric disorders, particularly in psychosis research, where modulation of glutamatergic signaling may provide therapeutic insights.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 2671063-84-4 |
| Applications | mGluR2 Modulator |
| Formula | C21H20F3N3O3 |
| Molecular Weight | 419.40 |
| SMILES | O=C1N(CCN2C1=NC3=C2C=CC=C3)CCCCOC4=CC=C(C=C4)OC(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.