mGluR2 modulator 1 is a potent positive allosteric modulator of the metabotropic glutamate receptor-2 (mGluR2), exhibiting an EC50 of 0.03 μM and effective blood-brain barrier penetration. This compound is valuable for investigating the role of mGluR2 in neuropsychiatric disorders, particularly in psychosis research, where modulation of glutamatergic signaling may provide therapeutic insights.
mGluR2 modulator 1 is a potent positive allosteric modulator of the metabotropic glutamate receptor-2 (mGluR2), exhibiting an EC50 of 0.03 μM and effective blood-brain barrier penetration. This compound is valuable for investigating the role of mGluR2 in neuropsychiatric disorders, particularly in psychosis research, where modulation of glutamatergic signaling may provide therapeutic insights.
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