Fig. 1 · Structure
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mGluR2 modulator 2
mGluR2 PAM
mGluR2 modulator 2 is a potent, selective positive allosteric modulator of the metabotropic glutamate receptor 2 (mGluR2), demonstrating an EC50 value of 0.13 μM. This compound enhances mGluR2 activity, making it a valuable tool for investigating its role in antipsychotic research. It is suitable for in vitro studies and can facilitate a deeper understanding of mGluR2-related pathways in various neuropsychiatric disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1004614-86-1 |
| Applications | mGluR2 PAM |
| Formula | C20H22FN3 |
| Molecular Weight | 323.41 |
| SMILES | CN1C2=CC=CC=C2N=C1CN3CCC(CC3)C4=CC=CC=C4F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.