Fig. 1 · Structure

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mGluR2 modulator 4

mGluR2 PAM

mGluR2 modulator 4 is a potent positive allosteric modulator of the metabotropic glutamate receptor 2 (mGluR2), exhibiting an EC50 value of 0.8 μM. This compound enhances receptor function and signaling, making it valuable for investigating antipsychotic mechanisms. Its application in research may provide insights into therapeutic strategies for psychiatric disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 2582758-47-0
Applications mGluR2 PAM
Formula C18H18BrN3
Molecular Weight 356.26
SMILES
BrC1=CC=C(C=C1)CCN2CCN3C4=CC=CC=C4N=C3C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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