Fig. 1 · Structure

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mGluR2 modulator 6

mGluR2 Modulator

mGluR2 modulator 6 is a selective modulator of the metabotropic glutamate receptor 2 (mGluR2), exhibiting significant anticonvulsant activity in the 6Hz epilepsy model. This compound has demonstrated enhanced efficacy when used in combination with Levetiracetam. It serves as a valuable tool for investigating the mechanisms underlying epilepsy and potential therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 1127498-73-0
Applications mGluR2 Modulator
Formula C20H23ClF2N2O
Molecular Weight 380.86
SMILES
O=C1C(Cl)=C(N2CCC(CC2)C3=CC=C(C=C3F)F)C=CN1CCCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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