Fig. 1 · Structure
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mGluR5 modulator 1
mGluR5 Positive Allosteric Modulator
mGluR5 modulator 1 is a positive allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5). This compound enhances mGluR5 receptor activity and is relevant for research into schizophrenia and cognitive impairments. Its ability to modulate glutamatergic signaling may provide insights into therapeutic strategies for neuropsychiatric disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1261171-52-1 |
| Applications | mGluR5 Positive Allosteric Modulator |
| Formula | C18H19ClFN3O2 |
| Molecular Weight | 363.81 |
| SMILES | FC1=CC(Cl)=CC=C1N2CCN(C(COCC3=CC=NC=C3)=O)CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.