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mGluR7 antagonist-2

mGluR7 Allosteric Antagonist

mGluR7 antagonist-2 is a potent and selective allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7), with an IC50 of 20 nM. This compound demonstrates significant selectivity for mGluR7 over other metabotropic glutamate receptors, including mGluR1, mGluR2, mGluR3, mGluR4, mGluR5, mGluR6, and mGluR8. mGluR7 antagonist-2 is valuable for research applications focusing on neuropharmacology and the investigation of glutamatergic signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	60986-80-3
Applications	mGluR7 Allosteric Antagonist
Formula	C₁₉H₁₄N₂O₂
Molecular Weight	302.33
SMILES	O=C1C2=C(C=C(N1C)C3=CC=CC=C3)ON=C2C4=CC=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.