mGluR7 antagonist-2 is a potent and selective allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7), with an IC50 of 20 nM. This compound demonstrates significant selectivity for mGluR7 over other metabotropic glutamate receptors, including mGluR1, mGluR2, mGluR3, mGluR4, mGluR5, mGluR6, and mGluR8. mGluR7 antagonist-2 is valuable for research applications focusing on neuropharmacology and the investigation of glutamatergic signaling pathways.
mGluR7 antagonist-2 is a potent and selective allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7), with an IC50 of 20 nM. This compound demonstrates significant selectivity for mGluR7 over other metabotropic glutamate receptors, including mGluR1, mGluR2, mGluR3, mGluR4, mGluR5, mGluR6, and mGluR8. mGluR7 antagonist-2 is valuable for research applications focusing on neuropharmacology and the investigation of glutamatergic signaling pathways.
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