MGS 0210

Catalog No.: A61911
mGluR2/3 Agonists
MGS 0210 is a potent mGluR2/3 agonist that demonstrates significant neuroprotective effects. This compound has been shown to enhance cognitive function and alleviate anxiety-related behaviors in animal models of Alzheimer's disease and post-traumatic stress disorder (PTSD). MGS 0210 serves as a valuable tool for investigating therapeutic strategies in various neurological disorders, including major depressive disorder and PTSD.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMGS 0210 is a potent mGluR2/3 agonist that demonstrates significant neuroprotective effects. This compound has been shown to enhance cognitive function and alleviate anxiety-related behaviors in animal models of Alzheimer's disease and post-traumatic stress disorder (PTSD). MGS 0210 serves as a valuable tool for investigating therapeutic strategies in various neurological disorders, including major depressive disorder and PTSD.
Product Information
Catalog NumA61911
FormulaC22H28Cl2FNO5
Molecular Weight476.37
CAS Number820244-38-0
SMILESCCCCCCCOC([C@@]1([C@]2([H])[C@@]1([H])C[C@@H](OCC3=CC(Cl)=C(Cl)C=C3)[C@@]2(N)C(O)=O)F)=O
SynonymsBCI 838
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