Fig. 1 · Structure
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MGS0274
mGlu2/mGlu3 Receptor Agonist
MGS0274 is an ester-based lipophilic prodrug targeting metabotropic glutamate (mGlu) receptors 2 and 3. It exhibits enhanced oral bioavailability compared to its parent compound, MGS0008. MGS0274 is valuable for investigating the role of mGlu2 and mGlu3 receptor modulation in schizophrenia research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1501974-69-1 |
| Applications | mGlu2/mGlu3 Receptor Agonist |
| Formula | C21H32FNO7 |
| Molecular Weight | 429.48 |
| SMILES | O=C([C@@]1(N)[C@]2([H])[C@@H](C(O[C@@H](OC(O[C@H]3[C@H](C(C)C)CC[C@@H](C)C3)=O)C)=O)[C@]2([H])C[C@@H]1F)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.