Fig. 1 · Structure
Documents & Downloads
mHTT-IN-1
mHTT Inhibitor
mHTT-IN-1 is a highly effective inhibitor of mutant huntingtin (mHTT), a protein implicated in the pathogenesis of Huntington's disease (HD). This compound demonstrates significant biological activity, exhibiting an EC50 value of 46 nM for the reduction of mHTT levels. mHTT-IN-1 is essential for research focused on elucidating the mechanisms of HD and developing potential therapeutic strategies targeting mHTT toxicity.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2839311-21-4 |
| Applications | mHTT Inhibitor |
| Formula | C18H19N7OS |
| Molecular Weight | 381.45 |
| SMILES | O=C1C=C(C2=NN3C=C(C)N=C3C(C)=C2)N=C4SC(N5CCNCC5)=CN14 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.