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mHTT ligand-1

mHTT Ligand

mHTT ligand-1 is a specific ligand for mutant huntingtin (mHTT), serving as a critical component in the development of PROTAC-based mHTT degraders. This reagent facilitates the design of targeted protein degradation strategies, such as PROTAC mHTT Degrader-1, which aim to address the pathophysiology of Huntington's disease. mHTT ligand-1 is an invaluable tool for researchers investigating therapeutic approaches to combat the deleterious effects of mHTT accumulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	1903786-86-6
Applications	mHTT Ligand
Formula	C₁₄H₁₄N₂O
Molecular Weight	226.27
SMILES	CNC1=CC=C(C=C1)/C=C/C2=CC=C(N=C2)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.