Biological Activity
MHY1485 is a mTOR activator; inhibits the autophagic process by inhibition of fusion between autophagosomes and lysosomes leading to the accumulation of LC3II protein and enlarged autophagosomes.
Targets
mTOR | ||||
In vitro | DMSO | 4 mg/mL (10.32 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.81 mL | 129.07 mL | 258.14 mL |
0.5 mM | 5.16 mL | 25.81 mL | 51.63 mL |
1 mM | 2.58 mL | 12.91 mL | 25.81 mL |
5 mM | 0.52 mL | 2.58 mL | 5.16 mL |
*The above data is based on the productmolecular weight 387.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15508 |
---|---|
Actions | Inhibitor |
CAS No. | 326914-06-1 |
Formula | C17H21N7O4 |
M. Wt | 387.39 |
Purity | >98% |
Synonyms | MHY 1485, MHY-1485 |
SMILES | C1COCCN1C2=NC(=NC(=N2)NC3=CC=C(C=C3)[N+](=O)[O-])N4CCOCC4 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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