MI-1061

Catalog No.: A18450

MDM2 inhibitor

MI-1061

MI-1061 Chemical Structure

CAS NO. 1410737-34-6

MI-1061 is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM; Ki=0.16 nM). MI-1061 potently activates p53, induces apoptosis, and has anti-tumor activity.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

MI-1061 is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM; Ki=0.16 nM). MI-1061 potently activates p53, induces apoptosis, and has anti-tumor activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.17 mL 85.84 mL 171.69 mL
0.5 mM 3.43 mL 17.17 mL 34.34 mL
1 mM 1.72 mL 8.58 mL 17.17 mL
5 mM 0.34 mL 1.72 mL 3.43 mL

*The above data is based on the productmolecular weight 582.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18450
Actions Inhibitor
M. Wt 582.45
Formula C30H26Cl2FN3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1410737-34-6
Synonyms MI1061, MI 1061
SMILES O=C(O)C1=CC=C(NC([[email protected]](N2)[[email protected]](C3=CC=CC(Cl)=C3F)[[email protected]]4(C(NC5=C4C=CC(Cl)=C5)=O)C62CCCCC6)=O)C=C1

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