Fig. 1 · Structure
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MI-nc dihydrochloride
Menin-MLL Inhibitor
MI-nc dihydrochloride is a weak inhibitor of the Menin-MLL interaction, exhibiting an IC50 value of 193 μM. This compound serves as a negative control for studies involving MI-2 and can be utilized in research exploring the role of Menin-MLL fusion proteins in oncogenesis. Its properties make it suitable for investigating therapeutic strategies in MLL-rearranged leukemia.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1934302-23-4 |
| Applications | Menin-MLL Inhibitor |
| Formula | C14H18Cl2N6S2 |
| Molecular Weight | 405.37 |
| SMILES | CCC1=CC2=C(N3CCN(C4=NN=CS4)CC3)N=CN=C2S1.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.