Fig. 1 · Structure
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Miclxin
MIC60 Inhibitor
Miclxin (DS37262926) is a potent inhibitor of MIC60, a key component of the mitochondrial contact site and cristae organizing system (MICOS) complex. By specifically targeting mutant β-catenin, Miclxin activates β-catenin-dependent apoptosis and induces significant mitochondrial dysfunction, characterized by loss of mitochondrial membrane integrity. This reagent is useful for research applications focused on Wnt signaling pathway modulation and its implications in tumor biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2494198-61-5 |
| Applications | MIC60 Inhibitor |
| Formula | C26H27N5O2 |
| Molecular Weight | 441.52 |
| Synonyms | DS37262926 |
| SMILES | COC1=CC(CNC2=C3C=CC(OC)=CC3=NC(N4CC(C5=CC=CN=C5)CC4)=N2)=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.