Fig. 1 · Structure

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Microginin 527

Angiotensin-converting Enzyme (ACE)

Microginin 527 is a linear cyanobacterial peptide that functions primarily as an angiotensin-converting enzyme (ACE) inhibitor. This compound demonstrates significant biological activity with an IC50 value of 31 μM, making it the most potent member in its class. In addition to its ACE inhibitory properties, Microginin 527 also affects protein phosphatases and leucine aminopeptidase. Its unique profile makes it a valuable tool for cardiovascular research and the study of blood pressure regulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1135249-50-1
Applications Angiotensin-converting Enzyme (ACE)
Formula C25H41N3O7S
Molecular Weight 527.67
SMILES
OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC([C@H](CCS(C)=O)N(C)C([C@@H](O)[C@@H](N)CCCCCCC)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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