Fig. 1 · Structure

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MID-1

MG53-IRS-1 Interaction Disruptor

MID-1 is an MG53-IRS-1 interaction disruptor. It inhibits the association between MG53 and IRS-1, resulting in the prevention of MG53-mediated IRS-1 ubiquitination and degradation in skeletal muscle. This activity leads to increased IRS-1 expression levels, enhancing insulin signaling and promoting glucose uptake, making MID-1 valuable for research focused on metabolic disorders and insulin resistance mechanisms.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 312608-54-1
Applications MG53-IRS-1 Interaction Disruptor
Formula C12H11N3O4S
Molecular Weight 293.30
SMILES
O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=C(OCC)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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