Fig. 1 · Structure

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Midaglizole

α2-Adrenoceptor Antagonist

Midaglizole, a potent α2-adrenoceptor antagonist, exhibits significant hypoglycemic activity. This compound is known to increase blood pressure while reducing blood glucose levels in vivo, making it a valuable tool in metabolic research. Its application extends to studies exploring the regulatory effects of adrenergic signaling on glucose metabolism and cardiovascular function.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 66529-17-7
Applications α2-Adrenoceptor Antagonist
Formula C16H17N3
Molecular Weight 251.33
Synonyms (±)-DG5128 free base; DG5128 free base
SMILES
C1(C(C2=CC=CC=C2)CC3=NCCN3)=NC=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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