Fig. 1 · Structure

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MIDD0301 sodium

Anti-asthmatic Agent

MIDD0301 sodium is a potent γ-aminobutyric acid type A receptor (GABAAR) inhibitor, serving as an effective anti-asthmatic agent. This compound demonstrates immunotoxicological safety in preclinical models and does not alter the counts of key circulating immune cells. MIDD0301 effectively relaxes histamine-induced contractions in guinea pig and human airway smooth muscle, making it valuable for research into bronchoconstrictive diseases. Its improved safety profile compared to traditional anti-inflammatory agents offers new avenues for therapeutic exploration in respiratory conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2593569-36-7
Applications Anti-asthmatic Agent
Formula C19H12BrFN3NaO2
Molecular Weight 436.21
Synonyms GL-II-93 sodium
SMILES
O=C(C1=C2N(C=N1)C3=CC=C(Br)C=C3C(C4=C(C=CC=C4)F)=N[C@@H]2C)O[Na]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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