MIK665

Catalog No.: A18362

Mcl-1 inhibitor

MIK665

MIK665 Chemical Structure

CAS NO. 1799631-75-6

MIK665 (S-64315) is a special Mcl-1 inhibitor extracted from patent WO2016207225A1, compound Preparation 13, has an IC50 of 1.81 nM.

Availability: In stock

Package Price Qty
5 mg
$300.00
10 mg
$500.00
50 mg
$1,500.00
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Biological Activity

MIK665 (S-64315) is a special Mcl-1 inhibitor extracted from patent WO2016207225A1, compound Preparation 13, has an IC50 of 1.81 nM.
In vitro DMSO 92 mg/mL (105.09 mM)
Water Insoluble
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.42 mL 57.12 mL 114.23 mL
0.5 mM 2.28 mL 11.42 mL 22.85 mL
1 mM 1.14 mL 5.71 mL 11.42 mL
5 mM 0.23 mL 1.14 mL 2.28 mL

*The above data is based on the productmolecular weight 875.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18362
Actions Inhibitor
CAS No. 1799631-75-6
Formula C47H44ClFN6O6S
M. Wt 875.41
Purity >98%
Synonyms MIK665; MIK-665; MIK 665; S 64315; S-64315; S64315
SMILES OC([[email protected]@H](CC(C=CC=C1)=C1OCC2=CC=NC(C3=CC=CC=C3OC)=N2)OC4=C5[[email protected]]([[email protected]]6=C(C)C(Cl)=C(OCCN7CCN(C)CC7)C=C6)=C(C8=CC=C(F)C=C8)SC5=NC=N4)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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