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MIK665 (S-64315) is a special Mcl-1 inhibitor extracted from patent WO2016207225A1, compound Preparation 13, has an IC50 of 1.81 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11.42 mL | 57.12 mL | 114.23 mL |
| 0.5 mM | 2.28 mL | 11.42 mL | 22.85 mL |
| 1 mM | 1.14 mL | 5.71 mL | 11.42 mL |
| 5 mM | 0.23 mL | 1.14 mL | 2.28 mL |
*The above data is based on the productmolecular weight 875.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18362 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 875.41 |
| Formula | C47H44ClFN6O6S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1799631-75-6 |
| Synonyms | MIK665; MIK-665; MIK 665; S 64315; S-64315; S64315 |
| SMILES | OC([[email protected]@H](CC(C=CC=C1)=C1OCC2=CC=NC(C3=CC=CC=C3OC)=N2)OC4=C5[[email protected]]([[email protected]]6=C(C)C(Cl)=C(OCCN7CCN(C)CC7)C=C6)=C(C8=CC=C(F)C=C8)SC5=NC=N4)=O |
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